منابع مشابه
High-dose antipsychotic medication.
The dopamine hypothesis for the mode of action of antipsychotic drugs has been with us for some 30 years and has, by and large, withstood the test of time. It simply states that antipsychotic drugs owe their therapeutic effects to an ability to block central dopamine receptors. This has given us a working and testable explanation for the effects of these drugs and it has prompted the synthesis ...
متن کاملAntipsychotic Medication and QT Prolongation
The QT interval represents ventricular depolarisation and repolarisation. Prolongation of this interval can lead to life-threatening complications. These can include arrhythmias such as Torsades de Pointes and Ventricular Fibrillation, which may ultimately lead to death. Many risk factors have been identified in prolonging the QT interval, one of which is medication commonly used in the treatme...
متن کاملAntipsychotic Medication and Diabetes Mellitus
Sir: Spoelstra and colleagues assert that antipsychotic drugs may worsen metabolic control in type 2 diabetes mellitus and speculate from their pharmacoepidemiologic study that this worsening is probably due to β-cell toxicity. While there is general agreement that exposure to antipsychotic medications (and second-generation agents in particular) may be associated with an increased risk of diab...
متن کاملAntipsychotic medication and diabetes mellitus.
Sir: Spoelstra and colleagues assert that antipsychotic drugs may worsen metabolic control in type 2 diabetes mellitus and speculate from their pharmacoepidemiologic study that this worsening is probably due to β-cell toxicity. While there is general agreement that exposure to antipsychotic medications (and second-generation agents in particular) may be associated with an increased risk of diab...
متن کاملMetabolic Disturbances with Antipsychotic Medication
! Increasing clinical experience with atypical antipsychotics has demonstrated an association between these medications and metabolic disturbances, including hyperglycaemia, diabetes mellitus, weight gain and dyslipidaemia. ! The term metabolic syndrome describes the incidence of a number of interrelated metabolic disturbances occurring in one patient and is becoming increasingly recognised as ...
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ژورنال
عنوان ژورنال: Advances in Psychiatric Treatment
سال: 1994
ISSN: 1355-5146,1472-1481
DOI: 10.1192/apt.1.1.16